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The Best Gyno In Surat Explains the Tests Required in Case of Multiple IVF Cycle Failures

When couples or individuals experience multiple IVF (in vitro fertilization) cycle failures, it can be emotionally and physically exhausting. However, understanding the possible causes behind these failures is essential to increasing the chances of success in future attempts, explains Dr Kaajal Mangukiya — founder of one of the best IVF hospitals in Surat — orkidmedilife Hospital and IVF Centre. Testing plays a crucial role in uncovering underlying issues that might be affecting the outcomes. In this blog, you’ll learn about the key tests recommended after repeated IVF failures and how they contribute to identifying and addressing potential problems.

1. Comprehensive Chromosomal Testing

Why It’s Important

Chromosomal abnormalities are a common cause of failed IVF cycles. Embryos with genetic issues may fail to implant or result in early miscarriages. By performing chromosomal testing, doctors can identify these issues and select healthier embryos.

Recommended Tests

● Preimplantation Genetic Testing (PGT): The best gyno in Surat recommend this to screen embryos for chromosomal abnormalities before implantation, ensuring only viable ones are transferred.

● Karyotyping: Both partners undergo this test to detect any chromosomal rearrangements or genetic conditions that could affect embryo development.

2. Uterine and Endometrial Evaluations

Why It’s Important

A healthy uterine environment is essential for successful embryo implantation. Structural abnormalities, infections, or poor endometrial receptivity can hinder the process.

Recommended Tests

● Hysteroscopy: This minimally invasive procedure examines the uterine cavity for polyps, fibroids, adhesions, or other abnormalities.

● Sonohysterography (Saline Infusion Sonography): Experts at the best IVF centre in Surat — Oorkid Hospital and IVF Centre — recommend this evaluation. It uses saline and ultrasound to provide detailed images of the uterus.

● Endometrial Receptivity Analysis (ERA): This test determines the optimal timing for embryo transfer by assessing the endometrium’s receptivity.

3. Thrombophilia and Clotting Disorders Testing

Why It’s Important

According to the doctors at the best test tube baby centre in Surat, blood clotting disorders can disrupt proper blood flow to the uterus, affecting implantation or early pregnancy development.

Recommended Tests

● Thrombophilia Screening: It identifies inherited or acquired clotting disorders, such as antiphospholipid syndrome or Factor V Leiden mutation.

● Complete Blood Count (CBC) with Coagulation Profile: This test evaluates blood cell counts and clotting factors.

4. Hormonal Testing

Why It’s Important

Hormonal imbalances can disrupt egg quality, ovulation, or the uterine environment, all of which are critical for IVF success.

Recommended Tests

● Thyroid Function Tests: Abnormal thyroid hormone levels can interfere with fertility.

● Prolactin Levels: Elevated prolactin can inhibit ovulation and affect reproductive hormones.

● Luteal Phase Defect Testing: This evaluation is suggested by the experts at the best infertility centres in Surat for testing progesterone levels to ensure sufficient support for early pregnancy.

5. Immune System Assessment

Why It’s Important

In some cases, an overactive or improperly functioning immune system may attack the embryo, preventing implantation, explains Dr Kaajal Mangukiya, one of the best gynos in Surat.

Recommended Tests

● Natural Killer (NK) Cell Testing: High levels or activity of NK cells can disrupt implantation.

● Antiphospholipid Antibody Testing: This detects antibodies that may cause recurrent implantation failure or miscarriages.

6. Male Factor Testing

Why It’s Important

Male fertility issues often go undiagnosed, but sperm quality plays a vital role in embryo development.

Recommended Tests

● Semen Analysis: This examines sperm count, motility, and morphology.

● DNA Fragmentation Testing: It evaluates sperm DNA integrity, as high fragmentation can lead to poor embryo quality.

● Y-Chromosome Microdeletion Testing: This identifies genetic defects in the Y chromosome that could affect fertility.

7. Lifestyle and Environmental Factors Analysis

Why It’s Important

Lifestyle choices and environmental exposures can influence fertility for both partners.

Recommended Steps

● Toxicology Screening: Exposure to heavy metals or toxins can impair reproductive health.

● Lifestyle Review: Doctors may evaluate factors such as smoking, alcohol use, stress, and diet.

How Testing Helps Improve Future IVF Success

Each of these tests contributes critical information that helps fertility specialists tailor treatments and optimize IVF protocols, according to the best gynaecologists in Surat. For instance:

● Embryo Selection: Chromosomal and mitochondrial testing helps prioritize embryos with higher chances of survival.

● Personalized Transfer Timing: ERA identifies the precise implantation window, improving synchronization between the embryo and the uterus.

● Corrective Treatments: Identifying hormonal imbalances, immune dysfunctions, or uterine issues allows targeted treatments, such as hormone therapy, anticoagulants, or surgery.

Conclusion

Facing multiple IVF failures can feel discouraging, but advanced diagnostic testing provides a path forward. By identifying hidden causes, fertility specialists can refine treatment plans, increase the likelihood of success, and provide renewed hope. If you’ve experienced repeated IVF failures, consult your doctor about these tests to take proactive steps toward achieving your dream of parenthood.

Diet Plan for the First Trimester of Pregnancy: What to Eat for a Healthy Start

The first trimester of pregnancy, covering weeks 1 through 12, is an incredibly formative period in fetal development. These weeks lay the foundation for your baby’s major organs and systems. A well-balanced, nutrient-dense diet can significantly impact the health of both you and your baby. Here’s a comprehensive guide from Dr Kaajal Mangukiya, founder of the best infertility centre in Surat — Oorkid hospital & IVF centre , to the essential nutrients, foods to include, and meal ideas for a nourishing first trimester diet plan.

Key Nutrients for the First Trimester

Your body undergoes significant changes to support the growth and development of your baby. Prioritizing the following nutrients can help promote a healthy pregnancy and ease some common symptoms like nausea and fatigue:

1. Folic Acid

Folic acid (or folate, in its natural form) is crucial in the first trimester as it helps prevent neural tube defects in the developing fetus. The best gynecologists in Surat recommend pregnant women to consume at least 400–800 micrograms of folic acid daily.

● Sources: Leafy greens (like spinach and kale), legumes (lentils and chickpeas), oranges, and fortified cereals.

2. Iron

Iron supports increased blood volume and helps supply oxygen to both mother and baby. Low iron levels can lead to fatigue and increase the risk of anemia.

● Sources: Lean meats, poultry, fish, fortified grains, spinach, and beans. Pair iron-rich foods with vitamin C sources, such as citrus fruits, for improved absorption.

3. Calcium and Vitamin D

Calcium is essential for fetal bone and tooth development, while vitamin D aids calcium absorption. Consuming adequate amounts of both can support healthy bone growth.

● Sources: Dairy products (like milk, yogurt, and cheese), leafy greens, fortified plant milks, and fatty fish, like salmon.

4. Protein

Protein is vital for the growth of fetal tissue, including the brain, and aids in the development of maternal tissue, especially in the uterus and breasts.

● Sources: Eggs, lean meats, tofu, beans, nuts, and seeds. Aim for about 70–100 grams of protein per day, depending on your weight and activity level.

5. Omega-3 Fatty Acids

Omega-3s, especially DHA, support brain and eye development in the fetus.

● Sources: Fatty fish (like salmon and sardines), walnuts, chia seeds, and flaxseeds. Choose low-mercury fish options to minimize risk.

6. Fiber

According toDr. Kaja; Mangukiya, one of the best gynos in Surat, constipation is a common first-trimester complaint due to hormonal changes. A diet rich in fiber helps keep digestion regular and can alleviate some discomfort.

● Sources: Whole grains, fruits, vegetables, beans, and legumes. Make sure to drink plenty of water to support fiber intake.

Sample First Trimester Diet Plan

Here’s a balanced, nutrient-rich sample diet plan to support your needs during the first trimester.

Breakfast

● Option 1: Vegetable Upma with rava (semolina) and vegetables like carrots, peas, and beans for fiber and vitamins. Serve with a spoon of ghee and a small bowl of curd for protein.

● Option 2: Ragi (Finger Millet) Porridge prepared with milk, topped with chopped almonds, walnuts, and a few raisins. This provides a good mix of calcium, protein, and essential minerals.

Mid-Morning Snack

● A bowl of homemade yogurt with a sprinkle of flaxseeds or chia seeds, providing calcium and omega-3 fatty acids or Amla/fresh orange juice for vitamin C for iron absorption

Lunch

● Option 1: Palak Paneer (spinach and cottage cheese) with one or two whole-grain rotis. Add a side of cucumber and carrot salad, and finish with a small serving of curd for probiotics.

● Option 2: Chole (chickpeas) curry with jeera rice and a mixed vegetable salad. This provides protein, fiber, and iron, especially when paired with a vitamin C-rich food.

Afternoon Snack

● Option 1: Fruit chaat with seasonal fruits (apple, pomegranate, orange) sprinkled with chaat masala for flavor.

● Option 2: A glass of masala buttermilk (chaas) with roasted cumin and coriander, which is refreshing and supports digestion.

Dinner

● Option 1: Baingan Bharta (roasted eggplant curry) with jowar or bajra rotis, served with a side of mixed vegetable sabzi.

● Option 2: Mixed Lentil Dal with a bowl of brown rice and a portion of stir-fried seasonal greens like methi (fenugreek) or bathua.

Foods to Avoid in the First Trimester

Certain foods carry risks of infection, toxins, or other adverse effects that can harm the developing fetus. Here’s what to avoid:

● Raw or undercooked meats, fish, and eggs: Risk of bacteria and foodborne illness.

● High-mercury fish: Limit intake of swordfish, king mackerel, and tilefish.

● Unpasteurized dairy and juices: Risk of listeria and other infections.

● Excessive caffeine: Limit to under 200 mg per day, roughly one 12-ounce cup of coffee.

● Alcohol: Avoid alcohol entirely, as it can lead to developmental issues.

Final Tips for First Trimester Nutrition

  1. Stay Hydrated: According to the doctors at Oorkid hospital & IVF centre, one of the best infertility hospitals in Surat, hormonal changes can lead to dehydration, so aim to drink at least 8–10 glasses of water daily.
  2. Balance Small, Frequent Meals: Eating small meals throughout the day can help manage nausea and prevent heartburn.
  3. Listen to Your Body: Pregnancy symptoms vary widely; choose foods that nourish and comfort you.

Reasons For IVF Failure: Understanding Them From The Best Gyno In Surat

In vitro fertilization (IVF) offers hope to many couples facing fertility challenges, but despite medical advances, IVF success rates are not guaranteed, and many couples experience failed cycles. In this blog, experts from orkid hospital & IVF centre, one of the best infertility hospitals in Surat, list down the reasons for IVF failure that can help in making informed decisions for future attempts.

1. Age of the Woman

One of the most influential factors in IVF success is the age of the woman undergoing the procedure. As women age, egg quality and quantity decline, and older eggs are more likely to have chromosomal abnormalities. Women over 35 experience a notable drop in IVF success rates, and by age 40, this decline is even more significant. Dr Kaajal Mangukiya, founder of the best IVF centres in Surat — orkid hospital & IVF centre — mentions poor egg quality as a major factor for embryos that fail to develop properly, making implantation and pregnancy less likely.

2. Embryo Quality

Embryo quality is a critical determinant of IVF success. Poor-quality embryos may fail to implant or develop, leading to a failed cycle. Chromosomal abnormalities, genetic defects, or damage during embryo handling can contribute to poor embryo quality. Embryologists assess embryos through grading, but high-grade embryos may still have genetic issues that prevent successful implantation. Preimplantation genetic testing (PGT) can help identify chromosomally healthy embryos, potentially improving the chances of success.

3. Uterine Issues and Endometrial Receptivity

For IVF to be successful, the uterus must be ready to receive and nourish the embryo, state the experts from the best IVF hospital in Surat — Oorkid hospital & IVF centre. Issues with the uterine environment, such as fibroids, polyps, or a thin endometrium, can hinder embryo implantation. Endometrial receptivity, which is the optimal period when the uterus is most conducive to implantation, can vary. Misalignment of the embryo transfer timing with endometrial receptivity is another factor that can lead to IVF failure. In some cases, a specialized test called the Endometrial Receptivity Array (ERA) can assess the best timing for embryo transfer.

4. Sperm Quality and Male Factor Infertility

While IVF often focuses on the female partner, male fertility also plays a critical role. Poor sperm quality, including issues with sperm motility, morphology, or DNA fragmentation, can impact embryo development. Male factor infertility can result in embryos with compromised genetic material, which may prevent successful implantation. Techniques like intracytoplasmic sperm injection (ICSI) can assist by injecting a single healthy sperm into each egg, improving the chances for fertilization in cases of male factor infertility.

5. Immune System Factors

The body’s immune response can also impact IVF success. Some women have immune-related issues where their body mistakenly identifies the embryo as a foreign entity and attacks it. Elevated natural killer (NK) cells or certain autoimmune conditions can prevent embryos from implanting in the uterus. Testing and treatment for immune issues, such as immunotherapy or steroid medication, can sometimes improve the chances of successful implantation from the best test tube baby centre in Surat for women with immune-related IVF challenges.

6. Lifestyle Factors

Certain lifestyle factors are known to impact IVF success rates. Smoking, excessive alcohol consumption, a poor diet, and a high body mass index (BMI) have all been linked to lower IVF success. Smoking, for example, damages egg quality, while high BMI can interfere with hormone levels and reduce ovarian response. Maintaining a balanced diet, moderate exercise, and stress management can support fertility and improve the chances of IVF success.

7. Laboratory and Technical Issues

IVF is a complex process requiring meticulous precision in a lab environment. Even slight deviations in lab conditions, equipment malfunction, or contamination can compromise embryo health and development. Selecting a reputable clinic with experienced staff and high lab standards can minimize the risk of technical errors that might lead to IVF failure.

8. Embryo Transfer Technique

The embryo transfer process itself is a delicate procedure that requires skill and precision. A poorly executed transfer, where the embryo is not positioned correctly in the uterus, can reduce the chances of implantation. The best gynos in Surat suggest ultrasound guidance during embryo transfer to improve placement accuracy, thereby enhancing the likelihood of success.

Final Thoughts

While IVF can be a complex journey with no guarantees, understanding the reasons for failure can provide clarity and offer a way forward. With advanced testing, lifestyle adjustments, and continued communication with the best gynecologists in Surat, couples can make informed decisions for their next steps. IVF challenges are common, but with perseverance and the right support, many couples find success in building the family they dream of.