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Month: June 2024

Exploring Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD): A Comprehensive Overview

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Advances in reproductive technology have opened up new possibilities for prospective parents, allowing them to take a proactive approach in ensuring the health and well-being of their future children. Among these innovations are Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD). Dr Kajal Mangukiya, founder of Orkid hospital & IVF Centre, one of the best IVF centre in Surat, explores these two powerful techniques that offer unprecedented insights into the genetic makeup of embryos before they are implanted.

Understanding PGS and PGD

Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD) are modern procedures performed in conjunction with In Vitro Fertilization (IVF). These techniques involve analysing cells from embryos created through IVF to identify potential genetic abnormalities or specific inherited genetic conditions.

Experts at Orkid Hospital, which is known as one of the best IVF hospital in Surat, use the PGS to screen for chromosomal abnormalities, such as Down syndrome or other aneuploidies, which can significantly impact the health and development of a child. By identifying embryos with the correct number of chromosomes, PGS can increase the chances of a successful pregnancy and a healthy birth.

On the other hand, PGD is used to diagnose specific genetic disorders or conditions that run in families. This technique can detect mutations or alterations in specific genes associated with conditions like cystic fibrosis, Huntington’s disease, sickle cell anaemia, and many others. PGD empowers couples at risk of passing on inherited genetic disorders to make informed decisions about which embryos to transfer, potentially reducing the likelihood of their child being affected by the condition, says Dr. Kajal Mangukiya, the best gyno in Surat, at Orkid hospital.

The PGS and PGD Process

Further explaining the process, Dr Kajal Mangukiya, our IVF specialist at Orkid Hospital, known as one of the best IVF hospitals in Surat, says that PGS and PGD typically begins with an IVF cycle, during which multiple eggs are retrieved from the intended mother and fertilized with the partner’s sperm in a laboratory setting. Once the embryos reach the appropriate stage of development, usually on the third or fifth day after fertilization, a small number of cells are carefully removed from each embryo for genetic analysis.

These cells are then subjected to specialized genetic testing techniques, such as Fluorescence In Situ Hybridization (FISH) or Next-Generation Sequencing (NGS), to analyse their chromosomal makeup or identify specific genetic mutations or alterations.

After the genetic analysis, embryos that are found to be chromosomally normal (in the case of PGS) or free from the specific genetic condition being tested for (in the case of PGD) are identified as candidates for transfer into the intended mother’s uterus.

It’s important to note that not all embryos may be suitable for transfer, as some may be affected by genetic abnormalities or conditions that could compromise their viability or the future health of the child.

Benefits of PGS and PGD

The potential benefits of PGS and PGD are multifaceted and can significantly impact the lives of prospective parents and their future children.

1. Increased Chances of Successful Pregnancy: By identifying and transferring chromosomally normal embryos through PGS, experts from the best test tube baby centre in Surat are of the opinion that couples experience higher rates of successful pregnancies and lower rates of miscarriage, as chromosomal abnormalities are a leading cause of pregnancy loss.

2. Reduced Risk of Genetic Disorders: PGD enables couples at risk of passing on specific genetic disorders to significantly reduce the likelihood of having a child affected by these conditions, providing peace of mind and potentially avoiding the emotional and financial burdens associated with managing these disorders.

3. Informed Decision-Making: Both PGS and PGD empower couples with valuable genetic information, allowing them to make informed decisions about their reproductive journey and future family planning.

4. Shorter Time to Conception: Some of the best gynaecologists in Surat, including Dr Kajal Mangukiya, say that by identifying the most viable embryos, PGS and PGD can potentially reduce the number of IVF cycles needed to achieve a successful pregnancy, saving time, emotional stress, and financial resources.

5. Psychological and Emotional Support: For couples at risk of passing on genetic disorders or those who have experienced recurrent miscarriages, PGS and PGD can offer a sense of control and reassurance, providing emotional support during a challenging time.

Navigating the Journey with Professional Guidance

The path of PGS and PGD requires careful consideration, education, and guidance from qualified healthcare professionals, such as reproductive endocrinologists, genetic counsellors, and fertility specialists.

These professionals along with the best gyno in Surat can provide personalized guidance, explain the processes, risks, and potential outcomes, and help couples make informed decisions that align with their values, beliefs, and goals.

Ultimately, PGS and PGD offer prospective parents the opportunity to take a proactive approach in ensuring the health and well-being of their future children. By leveraging these cutting-edge technologies and working closely with medical professionals, couples can navigate this journey with confidence and make informed choices that best suit their unique circumstances and aspirations.

Embrace Your Power: The Transformative Role of HIFU in Menopausal Women

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As women embark on the journey of menopause, a natural transition that marks the end of their reproductive years, they often encounter a range of challenges, such as the menopausal phase, that can profoundly impact their overall well-being. Fortunately, the field of medicine continues to evolve, offering innovative approaches to address these issues. In this blog, Dr Kajal Mangukiya, one of the best gyno in Surat, explains about one such breakthrough called the High-Intensity Focused Ultrasound (HIFU), a laser-based technology that is rapidly gaining recognition for its effectiveness and non-invasive nature in managing menopausal symptoms.

Understanding the Menopausal Experience

Menopause typically occurs between the ages of 45 and 55, although it can strike earlier or later for some women. This transformative phase is characterized by the cessation of menstruation and a significant decline in hormone levels, particularly oestrogen and progesterone. As these hormonal shifts occur, a multitude of symptoms can impact the daily life of women in unique ways.

From the all-too-familiar hot flashes and night sweats to the more intimate challenges of vaginal dryness and discomfort, menopause can be a physical and emotional rollercoaster. Urinary incontinence and urgency can further compound the discomfort, while mood swings, depression, and weight fluctuations add to the complexity of this life stage.

While some women may experience milder symptoms, others may find them debilitating, significantly impacting their quality of life. Experts from the best infertility centres in Surat, Orkid Hospital, say that traditional treatments, such as hormone replacement therapy (HRT), lifestyle changes, and over-the-counter remedies, can provide relief for many. However, these options are not universally suitable, and some women may experience side effects or prefer a more targeted approach.

Introducing HIFU: A Breakthrough in Menopausal Care

Enter High-Intensity Focused Ultrasound (HIFU), a cutting-edge, non-invasive therapeutic technique that harnesses the power of focused ultrasound waves to target specific tissues with remarkable precision. Initially developed for treating tumours, HIFU has since found applications in various medical fields, including cosmetic treatments and gynaecology.

At the heart of HIFU’s effectiveness lies its ability to deliver precise ultrasound energy to targeted areas, creating controlled thermal effects that stimulate tissue regeneration and collagen production, says dr. Kajal Mangukiya, one of the best gyno in Surat. In the context of menopause, HIFU is primarily utilized for vaginal rejuvenation, addressing symptoms such as dryness, laxity, and urinary incontinence — conditions that can significantly impact a woman’s self-confidence and overall well-being.

The HIFU Experience: Reclaiming Confidence and Vitality

At Orkid hospital & IVF Centre, one of the best infertility hospital in Surat, the HIFU treatment begins with a comprehensive consultation, during which a woman’s symptoms and medical history are carefully evaluated by our qualified healthcare professional. This crucial step ensures the suitability of HIFU treatment and provides a personalized approach to addressing her unique needs.

On the day of the procedure, patients undergo thorough preparation, receiving clear instructions and emotional support to ensure a comfortable and empowering experience. The treatment itself typically takes less than an hour and involves the insertion of a specially designed vaginal probe that emits focused ultrasound waves.

As the ultrasound energy penetrates the deeper layers of vaginal tissue, a controlled heating effect occurs, stimulating collagen production and tissue tightening. This process is meticulously monitored by medical professionals working at the best infertility centres in Surat, like the Orkid Hospital, ensuring precision and safety throughout the treatment.

One of the remarkable advantages of HIFU is its non-invasive nature. Unlike surgical options, there are no incisions or stitches involved, minimizing the risk of infection and speeding up recovery time. Patients can typically resume their normal activities immediately after the procedure, with only mild discomfort or swelling expected in the initial days.

Reclaiming Confidence and Well-Being

The benefits of HIFU for menopausal women extend beyond physical symptom relief. Clinical studies have demonstrated its effectiveness in significantly improving vaginal dryness, laxity, and urinary incontinence — conditions that can profoundly impact a woman’s self-esteem and overall quality of life.

By addressing these intimate concerns, HIFU empowers menopausal women to reclaim their confidence and embrace this life stage with renewed vigor, says Dr. Kajal Mangukiya, one of the best gynaecologist in Surat. The long-lasting results, often sustained through the stimulation of collagen production, provide a sense of lasting transformation and well-being.

Moreover, HIFU is generally considered safe, with a low risk of side effects, making it a well-tolerated option for those seeking a more targeted approach to menopausal symptom management.

Embracing Empowerment: A Journey of Self-Care

As women embark on this transformative journey with HIFU, it is essential to approach the experience with an empowered mindset. Menopause is a natural and beautiful transition, a rite of passage that should be celebrated and embraced with self-care and self-compassion.

By seeking out innovative solutions like HIFU, women are taking an active role in their well-being, reclaiming control over their bodies and their lives. This proactive approach not only addresses physical symptoms but also fosters a sense of empowerment and self-confidence that can resonate throughout every aspect of their lives.

The Future of Menopausal Care

As research and advancements in medical technology continue to evolve, menopausal care for women is poised for exciting developments. HIFU represents just the beginning of a wave of innovative solutions designed to address the unique challenges faced by women during this life transition.

According to our fertility expert at Orkid hospital, one of the best infertility hospital in Surat, embracing these cutting-edge treatments and fostering open dialogue about menopause, society can break down stigmas and create a supportive environment where women feel empowered to prioritize their well-being without compromise.

Whether you are navigating the early stages of menopause or seeking relief from long-standing symptoms, it is essential to consult with a qualified healthcare professional from the best gyno in Surat to explore your options. Together, you can embark on a personalized journey towards improved well-being, reclaiming your vitality and embracing this transformative chapter of life with grace and confidence.

Fertility Preservation: Know the Purpose, Your Options & Benefits

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“For many individuals, the ability to have children is a cherished dream. However, certain medical treatments or life circumstances can put that dream at risk by impacting one’s future fertility. This is where fertility preservation comes in — a proactive approach that aims to safeguard your chances of conceiving in the future”, says Dr Kajal Manguiya, one of the best gyno in Surat and founder of Orkid Hospital. In this blog post, we’ll explore the purpose of fertility preservation, the various options available, and the benefits it can offer.

Understanding the Purpose of Fertility Preservation

Fertility preservation refers to the process of preserving eggs, sperm, or reproductive tissues for future use. It is commonly recommended for individuals facing:

Cancer Treatment

Certain chemotherapy drugs, radiation, and surgical procedures can damage or destroy reproductive cells, potentially causing infertility.

Genetic Conditions

Those with genetic disorders that may impact future fertility may opt to preserve healthy eggs or sperm.

Age-Related Fertility Decline

As women age, their ovarian reserve (egg supply) diminishes, making conception more challenging.

Gender-Affirming Treatments

Transgender individuals may choose to preserve eggs or sperm before undergoing hormone therapy or gender-affirming surgeries.

Other Medical Conditions

Autoimmune disorders, premature ovarian failure, or recurrent ovarian cysts can also necessitate fertility preservation.

Doctors at Orkid Hospital, one of the best IVF centres in Surat, recommend fertility preservation because by preserving reproductive cells or tissues, individuals can potentially safeguard their ability to have biological children later in life, even after undergoing treatments that may compromise their fertility.

Fertility Preservation Options

Dr Kajal Mangukiya of Orkid Hospital, known as one of the best IVF hospitals in Surat, shares the various options available for fertility preservation, depending on the individual’s specific needs and circumstances:

Egg Freezing (Oocyte Cryopreservation)

This process involves stimulating the ovaries to produce multiple eggs, which are then retrieved and frozen for future use in in-vitro fertilization (IVF).

Embryo Freezing

Eggs are retrieved and fertilized with sperm in the laboratory, creating embryos that are then frozen for future transfer into the uterus.

Sperm Freezing

Sperm samples are collected and frozen, allowing future use in intrauterine insemination (IUI) or IVF procedures.

Ovarian Tissue Freezing

For prepubertal girls or women who cannot delay cancer treatment, ovarian tissue is surgically removed and frozen, preserving immature eggs.

Testicular Tissue Freezing

For prepubertal boys or men facing sterilizing treatments, testicular tissue is frozen to potentially restore fertility in the future.

The choice of preservation method depends on factors such as the individual’s age, fertility potential, medical condition, and personal preferences.

Benefits of Fertility Preservation

Experts at one of the best infertility centres in Surat, Orkid Hospital, share the benefits of fertility preservation:

Peace of Mind

Knowing that you have preserved your fertility can provide immense psychological relief, especially when facing treatments that may impact your ability to have children.

Expanded Family-Building Options

Preserved eggs, sperm, or embryos can be used in future assisted reproductive technologies (ARTs) like IVF or IUI, increasing your chances of having a biological child.

Genetic Continuity

By using your own preserved reproductive cells, you can ensure a genetic connection with your future offspring.

Timing Flexibility

Fertility preservation allows you to postpone parenthood until you are physically, emotionally, and financially ready, without worrying about age-related fertility decline.

Overcoming Medical Challenges

For those facing cancer or other conditions that may compromise fertility, preservation can offer a path to parenthood after successful treatment.

It’s important to note that while fertility preservation can significantly improve your chances of conceiving in the future, it does not guarantee a successful pregnancy. However, it does provide hope and the opportunity to explore various family-building options.

If you are facing medical treatments or life circumstances that may impact your fertility, it’s crucial to explore fertility preservation options early. Consult with a reproductive specialist at Orkid Hospital, one of the best test tube baby centres in Surat, to understand your specific situation and determine the best course of action to safeguard your dreams of parenthood.

Understanding the Reasons Behind Multiple IVF Failures: What to Do Next?

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You have gone through multiple cycles of IVF with high hopes of finally taking home a baby, only to face disappointment each time. The emotional and financial toll of failed IVF attempts can be devastating. However, do not lose heart just yet. Dr Kajal Mangukiya, one of the best gyno in Surat, helps us in understanding the potential reasons behind these recurrent failures and other options to explore at achieving your dream of parenthood.

Common Reasons for Multiple IVF Failures

Before delving into what you can do next, let’s examine some of the common factors that doctors at Orkid Hospital, one of the best IVF hospitals in Surat, say may be contributing to your IVF struggles:

1) Age

A woman’s age plays a crucial role in IVF success rates. As you grow older, egg quality and quantity diminish, making it harder to conceive. Multiple failed cycles could be an indication that it’s time to explore other options, such as using donor eggs.

2) Embryo Quality

At Orkid Hospital, well-known as one of the best IVF centres in Surat, doctors have seen patients where even with successful fertilization, the embryos may not develop properly or have genetic abnormalities, preventing implantation or leading to miscarriages. Advanced embryo testing and selection methods can improve your chances.

3) Implantation Issues

Sometimes, the embryo fails to implant in the uterine lining, or the lining itself is not optimally prepared for implantation. Your doctor may recommend additional tests or treatments to address any implantation barriers.

4) Male Factor Infertility

If the issue lies with sperm quality or count, your fertility specialist may suggest using donor sperm or advanced sperm retrieval and preparation techniques like ICSI (Intracytoplasmic Sperm Injection).

5) Underlying Medical Conditions

Certain medical conditions, such as endometriosis, polycystic ovary syndrome (PCOS), or uterine abnormalities, can affect fertility and IVF success rates. Treating these underlying issues at one of the best infertility centres in Surat, such as Orkid Hospital, may improve your chances.

6) Lifestyle Factors

Factors like stress, obesity, smoking, and excessive alcohol consumption can negatively impact IVF outcomes. Making positive lifestyle changes may be recommended.

7) Unexplained Infertility

In some cases, even after extensive testing, the cause of infertility remains unknown, making it more challenging to pinpoint the right course of action.

What to Do Next After Multiple Failed IVF Cycles

If you have experienced multiple IVF failures, do not lose hope. Here are some steps you can take to increase your chances of success:

1) Seek a Second Opinion

Consider consulting with another fertility specialist or reproductive endocrinologist at one of the best test tube baby centres in Surat. A fresh perspective and different expertise may uncover new insights or treatment approaches you haven’t tried before. We at Orkid Hospital are always there for you and provide you with the best consultation.

2) Explore Advanced Diagnostic Testing

Your doctor may recommend additional tests to identify any underlying issues that could be contributing to the failures. These may include genetic testing, uterine evaluations, or immune system assessments.

3) Consider Assisted Hatching or Embryo Testing

Techniques like assisted hatching (where the embryo’s outer shell is thinned to aid implantation) or preimplantation genetic testing (PGT) can improve embryo selection and increase the chances of a successful pregnancy.

4) Try Natural or Mild IVF Cycles

In some cases, your doctor may suggest attempting a more natural or mild IVF cycle, which involves using lower doses of fertility medications. This approach can be gentler on your body and may yield better results.

5) Discuss Using Donor Eggs or Sperm

If age or genetic factors are the primary obstacles, using donor eggs or sperm could significantly increase your chances of success. While emotionally challenging, this option can help overcome certain fertility barriers.

6) Consider Gestational Surrogacy

If you have struggled with implantation issues or have a medical condition that makes carrying a pregnancy difficult, gestational surrogacy could be an alternative path to parenthood.

7) Explore Adoption or Other Family-Building Options

For some couples, the emotional and financial toll of repeated IVF failures may lead them to consider adoption or other family-building options, such as fostering or choosing to live child-free.

8) Seek Emotional Support

Dealing with multiple IVF failures can be emotionally draining. Consider joining a support group, seeking counselling, or confiding in loved ones to help you cope with the stress and disappointment.

Remember, every couple’s journey is unique, and what works for one may not work for another. By maintaining open communication with your fertility specialist, being proactive in exploring different options, and seeking emotional support, you can increase your chances of overcoming these obstacles and achieving your dream of starting or expanding your family.

The Future of Vaginal Health: HIFU (Laser)

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Vaginal health is a crucial aspect of overall well-being for women. As we continue to advance in medical technology, innovative treatments are emerging to address various vaginal health concerns. One such ground-breaking approach is High Intensity Focal Ultrasound (HIFU), which offers non-invasive solutions for vaginal rejuvenation. Dr Kajal Mangukiya, founder of Orkid Hospital and one of the best gyno in Surat, helps us in understanding how HIFU is poised to become the most sought after treatment for vaginal health. Let’s go!

Understanding HIFU

High-Intensity Focused Ultrasound (HIFU) is a non-invasive therapeutic technique that uses focused ultrasound waves to generate heat, targeting specific tissues without damaging surrounding areas. Initially used in oncology to treat tumours, HIFU has expanded into cosmetic and gynaecological applications. The technology works by delivering high-frequency ultrasound waves to precise areas, causing thermal coagulation and tissue remodelling.

Vaginal Health: Current Challenges

Vaginal health is a critical aspect of women’s overall well-being, yet it often remains a taboo topic. Many women suffer in silence from conditions such as vaginal atrophy, laxity, and urinary incontinence, which can significantly impact their quality of life. Traditional treatments, including hormone therapy and surgical interventions, come with their own sets of risks and limitations. Hormone therapy, for instance, is not suitable for all women, particularly those with a history of hormone-sensitive cancers. Surgical options, while effective, involve longer recovery times and potential complications.

HIFU: A Game-Changer in Vaginal Health

HIFU offers a promising alternative to traditional treatments. Its non-invasive nature, combined with its precision, makes it an attractive option for addressing various vaginal health issues. Here’s how HIFU at Orkid Hospital – one of the best infertility centres in Surat, is set to revolutionize vaginal health:

 

Vaginal Tightening and Rejuvenation

One of the most popular uses of HIFU in gynaecology is for vaginal tightening and rejuvenation. As women age or after childbirth, the vaginal walls can lose elasticity and strength, leading to discomfort and a decrease in sexual satisfaction. HIFU stimulates collagen production, enhancing the structural integrity and elasticity of the vaginal tissue. Women who undergo HIFU treatment report improved sexual function and increased confidence.

Treatment of Vaginal Atrophy

Vaginal atrophy, characterized by thinning, drying, and inflammation of the vaginal walls, affects many postmenopausal women. It can cause discomfort, pain during intercourse, and recurrent urinary infections. Doctors at Orkid Hospital, one of the best infertility hospitals in Surat, have seen HIFU helping as a non-hormonal treatment option that rejuvenates the vaginal tissue, alleviating symptoms and improving vaginal health. The thermal effect of HIFU increases blood flow and promotes tissue regeneration, restoring the vaginal mucosa to a healthier state.

Addressing Urinary Incontinence

Urinary incontinence, particularly stress urinary incontinence, is a common issue that affects millions of women worldwide. Traditional treatments range from pelvic floor exercises to surgery. HIFU offers a less invasive alternative by strengthening the pelvic floor muscles and supporting structures around the urethra. This treatment can significantly reduce or even eliminate symptoms of urinary incontinence, providing women with a better quality of life.

Advantages of HIFU

According to our experts at Orkid Hospital, being one of the best infertility hospital in Surat, the advantages of HIFU over traditional treatments are manifold:

Non-Invasive and Painless:

HIFU treatments are non-invasive, requiring no incisions or anaesthesia. This means no downtime and minimal discomfort during and after the procedure.

Quick and Convenient:

The procedure typically takes about 30 to 60 minutes, making it possible for women to undergo treatment during a lunch break and return to their daily activities immediately.

Long-Lasting Results:

HIFU stimulates natural processes in the body, such as collagen production, leading to long-lasting results. Women can experience benefits for months or even years after treatment.

Minimal Side Effects:

Unlike hormone therapy, HIFU has minimal side effects. Some women may experience mild redness or swelling, but these symptoms are temporary and usually resolve within a few days.

The Future Landscape

As more clinical studies validate the efficacy and safety of HIFU for vaginal health, its adoption is likely to increase. Innovations in HIFU technology are continually improving precision and outcomes, making treatments even more effective. Additionally, as awareness grows, more women will feel empowered to seek help for their vaginal health issues, breaking down the stigma surrounding these conditions.

As one of the best gyno in Surat, Dr Kajal Mangukiya shares, “We can anticipate further integration of HIFU into mainstream gynaecological practice. This will not only provide women with more options but also set a new standard for treating vaginal health issues. The development of portable HIFU devices could make treatments more accessible, allowing women to receive care in various settings, including clinics and even at home.”

Conclusion

HIFU represents a significant leap forward in the field of vaginal health. Its non-invasive nature, combined with its effectiveness in treating a range of conditions, positions it as a game-changer. As we look to the future, HIFU holds the promise of improving the lives of countless women, offering them a safe, effective, and convenient option for maintaining their vaginal health. Embracing this technology can lead to a future where women’s health issues are addressed openly, with innovative solutions that enhance their quality of life.